Köckerling F, Lorenz R, Hukauf M, Grau H, Jacob D, Fortelny R, Koch A.

Influencing Factors on the Outcome in Female Groin Hernia Repair: A Registry-based Multivariable Analysis of 15,601 Patients.

Ann Surg. Jul;270(1):1-9,2019

Köckerling F, Jacob DA, Wiegank W, Hukauf M, Schug-Pass C, Kuthe A, Bittner R
Endoscopic repair of primary vs recurrent male unilateral inguinals hernias – Are there differences in the outcome?
Surg Endosc 30(3): 1146-55,  2016

Köckerling F, Bittner R, Jacob DA, Schug-Pass C, Seidelmann L, Keller T, Adolf D, Kuthe A
TEP vs TAPP: Comparison of the perioperative outcome in 17,587 patients with a primary unilateral inguinal hernia
Surg Endosc 29(12): 3750-60,  2015

Jacob DA, Hackl J, Bittner R, Kraft B, Köckerling F
Perioperative outcome of unilateral versus bilateral inguinal hernia repairs in TAPP technique: analysis of 15,176 cases from the Herniamed Registry.
Surg Endosc 29(12): 3722-40, 2015

Köckerling F, Bittner R, Jacob D, Schug-Pass C, Laurenz C, Adolf D, Keller T, Stechemesser B
Do we need antibiotic prophylaxis in endoscopic inguinal hernia repair? – Results of the Herniamed Registry
Surg Endosc 29(12): 3741-9, 2015

Klein F, Jacob DA, Bahra M, Pelzer U, Puhl G, Andreou A, Guel S, Guckelberger O
Prognostic factors for long-term survival in patients with ampullary carcinoma-the results of a 15 year observation period after pancreaticoduodenectomy
Hepatobiliary and Pancreatic Surgery
Hepato-Pancreato-Biliary Surgery (epub) Mar 2014

Köckerling F, von Rosen T, Jacob DA
A new plug repair technique for anal fistula
Frontiers in Surg., doi: 10.3389/fsurg.2014.00017 Mai 2014

Schug-Pass C, Jacob DA, Lippert H, Köckerling F
Differences in biomechanical stability using various fibrin glue compositions for mesh fixation in endoscopic inguinal hernia repair.
Surgical Endoscopy 26(11): 3282-3286, 2012

*Schug-Pass C, *Jacob DA, Rittinghausen J, Lippert H, Köckerling F
Biomechanical properties of (semi-) synthetic glues for mesh fixation in hernia surgery
Hernia 17(6): 773-777, 2013
*both authors are contributed equally

Köckerling F, Grund S, Jacob DA
Typische intraoperative Komplikationen in der laparoskopischen Chirurgie
Der Chirurg 83(7): 633-641, 2012

Klein F, Bahra M, Glanemann M, Faber W, Warnick P, Andreou A, Gul S, Jacob DA
Matched-pair analysis of postoperative morbidity and mortality for pancreaticogastrostomy and pancreaticojejunostomy using mattress sutures in soft pancreatic tissue remnants
Hepatobiliary Pancreat Dis Int 11(1):89-95, 2012

*Stechemesser B, *Jacob DA, Schug-Paß C, Köckerling F
Herniamed: An internet-based registry for outcome research in hernia surgery
Hernia 16(3): 239-250, 2012
*both authors are contributed equally

Jacob DA, Schug-Paß C, Sommerer F, Tannapfel A, Lippert H, Köckerling F
Comparison of a lightweight polypropylene mesh (Optilene LP) and a large pore knitted PTFE mesh (Infinit) – biocompatibility in a standardized endoscopic extraperitoneal hernia model.
Langenbecks Arch Surg 397(2):283-289, 2012

Jacob DA, Raakow R
Single-port versus multi-port cholecystectomy for acute cholecystitis:
a retrospective comparative analysis
Hepatobiliary Pancreat Dis Int 10(5): 521-525, 2011

Raakow R, Jacob DA
Single-Incision Cholecystectomy in about 200 patients
Minim Invasive Surg
Volume 2011, Article ID 915735, 5 pages doi:10.1155/2011/915735, 2011

Jacob DA, Bahra M, Neuhaus P, Schumacher G
Konservative Therapie multipler Leberabszesse bei Arteria hepatica Verschluss
nach Lebertransplantation
Viszeralmedizin 27(2): 162-165, 2011

Kohler I*, Jacob D*, Budzies J, Lehmann A, Weichert W, Schulz S, Neuhaus P, Röcken C
The phenotypic and genotypic diversity of carcinomas of the papilla of Vater correlate with patient prognosis
Am J Clin Pathol, 135(2): 201-211, 2011
* both authors are contributed equally

Raakow R, Jacob DA
Initial experience in laparoscopic single-port appendectomy:
A pilot study
Dig Surg 28(1): 74-79, 2011

Jacob DA, Raakow R
Transumbilikale single-port Appendektomie:
Erste Ergebnisse und technische Beschreibung.
Zentralbl Chirurgie 138(3): 309-12,  2013

Jacob DA, Raakow R
Single-port Cholezystektomie: Der neue Standard?
Dtsch Med Wochenschr, 135(27): 1363-1367, 2010

Jacob DA, Haase E, Klein F, Pratschke J, Neumann UP, Neuhaus P, Bahra M
Donor influence on outcome in patients undergoing liver transplantation for PBC
Exp Clin Transplant, 8(2): 104-110, 2010

Jacob DA, Haase N, Lindner T, Haase T
Extraartikuläre rezidivierende Blutung aus dem medialen Retinaculumbereich.
Z Orthop Unfall, 148(5): 579-580, 2010

Glanemann M, Shi B, Liang F, Sun XG, Bahra M, Jacob D, Neumann U, Neuhaus P
Surgical strategies for treatment of malignant pancreatic tumors: extended,
standard or local surgery?
World J Surg Oncol 12;6(1):123, 2008

Bahra M, Jacob D, Langrehr JM, Glanemann M, Schumacher G, Lopez-Hanninen E,
Neuhaus P
Metastatic lesions to the pancreas. When is resection reasonable?
Chirurg 79: 241-248, 2008

Bahra M, Jacob D, Langrehr JM, Neumann UP, Neuhaus P
Carcinoma of the distal and middle bile duct: surgical results, prognostic factors, and long-term follow-up.
J Hepatobiliary Pancreat Surg 15: 501-507, 2008

Jacob DA, Bahra M, Schmidt SC, Schumacher G, Weimann A, Neuhaus P, Neumann UP
Mayo risk score for primary biliary cirrhosis: A useful tool for the prediction of course after liver transplantation?
Ann Transplant, 13: 35-42, 2008

Bahra M*, Jacob DA*, Neumann UP, Langrehr JM, Neuhaus R, Neuhaus P
Influence of donor histology on outcome in patients undergoing transplantation for hepatitis C.
Transplantation, 84(2): 144-148, 2007
* both authors are contributed equally

Jacob DA*, Marcus Bahra*, Jan M Langrehr, Sabine Boas-Knoop, Robert Stefaniak, John Davis, Guido Schumacher, Steffen Lippert, Ulf Neumann
Combination therapy of Poly (ADP-ribose)polymerase inhibitor 3-aminobenzamide and gemcitabine shows strong antitumor activity in pancreatic cancer cells.
Journal of Gastroenterology & Hepatology; 22(5): 738-748, 2007
* both authors are contributed equally

Schumacher G, Hoffmann J, Cramer T, Spinelli A, Jacob D, Bahra M
Antineoplastic activity of 2-methoxyestradiol in human pancreatic and gastric cancer cells with different multidrug-resistant phenotypes.
J Gastroenterol Hepatol 22: 1469-1473, 2007

Bahra M, Jacob D, Thelen A, Neumann UP
Oberbaucheviszeration beim fortgeschrittenen hepatopankreatischen
Chir Gastroenterol 23: 367-373, 2007

Schmidt SC, Hamann S, Langrehr JM, Hoflich C, Mittler J, Jacob D, Neuhaus P
Preoperative high-dose steroid administration attenuates the surgical stress
response following liver resection: results of a prospective randomized study.
J Hepatobiliary Pancreat Surg, 14(5):484-492, 2007

Schmidt SC, Pohle C, Langrehr JM, Schumacher G, Jacob D, Neuhaus P
Laparoscopic-assisted placement of peritoneal dialysis catheters: implantation
technique and results.
J Laparoendosc Adv Surg Tech A, 17(5): 596-599, 2007

Schumacher G., Eisele R, Spinelli A, Schmidt SC, Jacob D, Pratschke J, Neuhaus P
Indications for hand-assisted laparoscopic radiofrequency ablation for liver tumors.
J Laparosendosc Adv Surg Tech A, 17(2): 153-159, 2007

Schumacher G, Weidemann H; Langrehr JM, Jonas S, Mittler J, Jacob D, Schmidt SC, Spinelli A, Pratschke J, Pfitzmann R, Alekseev D, Neuhaus P
Transabdominal ligation of the thoracic duct as treatment of choice for
postoperative chylothorax after esophagectomy
Disease of the esophagus, 20(1): 19-23, 2007

Bahra M, Neumann UP, Jacob D, Langrehr JM, Berg T, Neuhaus R, Neuhaus P
Fibrosis progression in hepatitis C positive liver recipients following sustained virological response to antiviral combination therapy (interferon-ribavirin therapy)
Transplantation, 83(3): 351.-353, 2007

Bahra M, Jacob DA, Pascher A, Plockinger U, Kristiansen G, Neuhaus P, Langrehr JM
Surgical strategies and predictors of outcome for malignant neuroendocrine tumors of the pancreas.
Journal of Gastroenterology & Hepatology, 22(6): 930-935, 2007

Jacob DA, Neumann UP, Bahra M, Langrehr JM, Neuhaus P
Lebertransplantation bei Primär Biliärer Zirhhose:
Retrospektive Analyse eines Zentrums.
Deutsche Medizinische Wochenschrift, 131(42): 2327-2332, 2006

Jacob DA, Bahra M, Langrehr JM
External drainage of pancreatic juice after pancreatic head resection: A comparison between jejunal loop and direct pancreatic duct drainage.
Surgery Today, 36(10): 898-907, 2006

Jacob DA, Neumann UP, Bahra M, Klupp J, Puhl G, Neuhaus R, Langrehr JM
Long-term follow-up after recurrence of primary biliary cirrhosis after liver transplantation in 100 patients.
Clinical Transplantation, 20 (2):211-20, 2006

Lindner T, Bail H, Heise M, Schmidt SC, Jacob D, Haas NP, Stockle U
Traumatic aneurysm of the superior mesenteric artery associated with a burst-fracture of the second lumbar spine – Unforeseen sequelae of a fall from a ladder.
Unfallchirurg, 109(2):160-4, 2006

Jacob D, Schumacher G, Bahra M, Davis J, Zhu H, Zhang L, Teraishi F, Neuhaus P, Fang B
Fiber-modified adenoviral vector expressing the tumor necrosis factor-related apoptosis-inducing ligand gene from the human telomerase reverse transcriptase promoter induces apoptosis in human hepatocellular carcinoma cells.
World Journal of Gastroenterology, 11(17): 2552-2556, 2005

Langrehr JM, Bahra M, Jacob D, Glanemann M, Neuhaus P
Prospective randomized comparison between a new mattress technique and Cattell (duct-to-mucosa) pancreaticojejunostomy for pancreatic resection.
World Journal of Surgery, 29 (9): 1111-1119, 2005

Bahra M, Neumann UP, Jacob D, Langrehr JM, Neuhaus P
Repeated steroid pulse therapies in HCV-positive liver recipients: significant risk factor for HCV-related graft loss.
Transplantation Proceedings, 37(4): 1700-1702, 2005

Jacob DA, Neumann UP, Bahra M, Langrehr JM, Neuhaus P
Liver transplantation for Primary Biliary Cirrhosis: Influence of primary immunosuppression. on survival.
Transplantation Proceedings, 37(4): 1691-1692, 2005

Schumacher G, Oidtmann M, Rueggeberg A, Jacob D, Jonas S, Langrehr JM, Neuhaus R, Bahra M, Neuhaus P
Sirolimus inhibits growth of human hepatoma cells alone or combined with tacrolimus, while tacrolimus promotes cell growth.
World Journal of Gastroenterology, 11(10): 1420-1425, 2005

Loew A, Jacob D, Neuhaus P, Riess H
Resistance to activated protein c caused by factor V Leiden mutation and orthotopic liver transplantation.
Transplantation, 79(10); 1422-1427, 2005

Jacob DA, Davis J, Schumacher G, Bahra M, Neuhaus P, Fang B
Gentherapie durch einen RGD modifizierten, hTERT regulierten, TRAIL exprimierenden adenoviralen Vektor in malignen Tumoren.
Zeitschrift für Gastroenterologie, 42(12):1363-70, 2004

Zhu H, Zhang L, Huang X, Davis JJ, Jacob DA, Teraishi F, Chiao P, Fang B
Overcoming acquired resistance to TRAIL by chemotherapeutic agents and calpain inhibitor I through distinct mechanisms.
Molecular Therapy, 9: 666-673, 2004

Wu S, Zhu H, Gu J, Zhang L, Teraishi F, Davis JJ, Jacob DA, Fang B
Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-Dichlorophenoxy)propyl]amino]ethanol.
Cancer Research, 64: 1110-1113, 2004

Zhang L, Zhu H, Davis JJ, Jacob DA, Wu S, Teraishi F, Gutierrez A, Wang Y, Fang B
Lack of p38 MAP kinase activation in TRAIL-resistant cells is not related to the resistance to TRAIL-mediated cell death.
Cancer Biology & Therapy, 3: 296-301, 2004

Jacob DA, Davis J, Fang B
Xenograftic tumor models in mice for cancer research, a technical review.
Gene Therapy & Molecular Biology, 8: 213-219, 2004

Wu S, Zhu H, Gu J, Zhang L, Teraishi F, Davis JJ, Jacob DA, Fang B
Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-Dichlorophenoxy)propyl]amino]ethanol.
Cancer Research, 64: 1110-1113, 2004

Zhang L, Zhu H, Davis JJ, Jacob DA, Wu S, Teraishi F, Gutierrez A, Wang Y, Fang B
Lack of p38 MAP kinase activation in TRAIL-resistant cells is not related to the resistance to TRAIL-mediated cell death.
Cancer Biology & Therapy, 3: 296-301, 2004

Jacob D, Bahra M, Schumacher G, Neuhaus P, Fang B
Gene therapy of colon cancer cells with a fiber-modified adenovector expressing the TRAIL gene driven by the hTERT promoter.
Anticancer Research, 24(5A): 3075-9, 2004

Zhu H, Zhang L, Wu S, Teraishi F, Davis JJ, Jacob D, Fang B
Induction of S-phase arrest and p21 overexpression by a small molecule 2[[3-(2,3-dichlorophenoxy)propyl] amino]ethanol in correlation with activation of ERK.
Oncogene, 23(29): 4984-4992, 2004

Jacob D, Davis J, Zhang L, Zhu H, Teraishi F, Fang B
Suppression of pancreatic tumor growth in the liver by systemic administration of the TRAIL gene driven by the hTERT promoter.
Cancer Gene Therapy, 12(2): 109-115, 2004

Jacob D, Davis J, Zhu H, Zhang L, Teraishi, Wu S, Marini FC, Fang B
Suppressing Orthotopic Pancreatic Tumor Growth with a Fiber modified Adenovector Expressing the TRAIL Gene from the hTERT Promoter.
Clinical Cancer Research, 10: 3535-3541, 2004

Jacob D, Schumacher G, Langrehr JM, Bahra M, Davis J, Marini FC, Neuhaus P und Fang B
Tumorsuppression durch ein RGD modifiziertes, hTERT reguliertes, TRAIL exprimierendes Adenovirus in einem orthotopen Pankreas Tumormodel.
Forumband 33: 123-125, 2004

Bahra M, Neumann UP, Harren M, Jacob D, Langrehr JM, Berg T, Neuhaus R, Neuhaus P
Significance of mycophenolate mofetil treatment in patiens with HCV reinfection after liver transplantation: impact on clinical course and histologic damage.
Transplantation Proceedings: 34: 2934-2935, 2002

Schumacher G, Oidtmann M, Rosewicz S, Langrehr JM, Jonas S, Mueller AR, Rueggeberg A, Neuhaus R, Bahra M, Jacob D, Gerlach H, Neuhaus P
Sirolimus inhibits growth of human hepatoma cells in contrast to tacrolimus which promotes cell growth.
Transplantation Proceedings.;34: 1392-1393, 2002

Walldorf J, Platz KP, Jacob D, Horstmann M, Neuhaus P, Müller AR
sICAM, sVCAM and sE-Selectin May Be Useful Predictors of Postoperative Complications After Major Abdominal Surgery.
5th World Congress on Trauma, Shock, Inflammation and Sepsis,
Editor Eugen Faist, Monduzzi Editore: 431-435, 2000

Jacob D, Müller AR, Walldorf J, Horstmann M, Neuhaus P, Platz KP
IL-8 and IL-10 as Marker for Postoperative Complications after Abdominal surgery.
5th World Congress on Trauma, Shock, Inflammation and Sepsis,
Editor Eugen Faist, Monduzzi Editore: 431-435, 2000